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Updated: 2017 Aug. 1

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Warning – Occasionally the phosphosites shown below in more divergent species may be slightly mis-aligned with our algorithm and the calculated Conservation Score may be higher than shown.
Phosphosite   Conservation Score
Human Protein: NEK11 All Species: 12.73
Human Site: T302 Identified Species: 28
UniProt: Q8NG66 Number Species: 10
    Phosphosite Substitution
    Charge Score: 0
Phosphosite
Sequences
Species Species
Scientific Name
UniProt ID NCBI Ref Seq ID AA# Mr(Da) P-Site -7 -6 -5 -4 -3 -2 -1 0 1 2 3 4 5 6 7
Human Homo sapiens Q8NG66 NP_001139475.1 645 74162 T302 M C R Y S E M T L E D K N L D
Chimpanzee Pan troglodytes XP_001146942 470 54021 V164 R D L K S K N V F L K N N L L
Rhesus Macaque Macaca mulatta XP_001115725 637 73261 T302 M C R H S E M T L E D K N L D
Dog Lupus familis XP_542780 746 83424 T422 M C R Y S E M T L E N K N L N
Cat Felis silvestris
Mouse Mus musculus Q8C0Q4 628 71648 T303 M C K Y P E M T L E D K N S V
Rat Rattus norvegicus NP_001101652 507 57337 A201 P Y Y M S P E A L K H Q G C D
Wallaby Macropus eugenll
Platypus Ornith. anatinus XP_001514341 605 69266 Q290 K S P Y I D A Q L Q H M K C K
Chicken Gallus gallus XP_414252 807 90823 N470 V S L D S T E N L L G P F V P
Frog Xenopus laevis Q7ZZC8 944 104521 M303 D M E E K V S M L N R S N K K
Zebra Danio Brachydanio rerio Q90XC2 697 76523 R334 S G I S T P L R L P M L N T E
Tiger Blowfish Takifugu rubipres
Fruit Fly Dros. melanogaster
Honey Bee Apis mellifera
Nematode Worm Caenorhab. elegans
Sea Urchin Strong. purpuratus
Poplar Tree Populus trichocarpa
Maize Zea mays
Rice Oryza sativa
Thale Cress Arabidopsis thaliana Q9CAU7 606 68016 E285 P A Q W P E S E S A R R N S F
Baker's Yeast Sacchar. cerevisiae
Red Bread Mold Neurospora crassa
Conservation
Percent
Protein Identity: 100 72.4 94.1 69 N.A. 72.5 57.8 N.A. 67.9 27.1 20.7 23.5 N.A. N.A. N.A. N.A. N.A.
Protein Similarity: 100 72.5 95.9 75.4 N.A. 81 67.9 N.A. 78.2 46.7 38.9 42.9 N.A. N.A. N.A. N.A. N.A.
P-Site Identity: 100 20 93.3 86.6 N.A. 73.3 20 N.A. 13.3 13.3 13.3 13.3 N.A. N.A. N.A. N.A. N.A.
P-Site Similarity: 100 26.6 100 100 N.A. 80 33.3 N.A. 26.6 26.6 13.3 33.3 N.A. N.A. N.A. N.A. N.A.
Percent
Protein Identity: N.A. N.A. N.A. 23.1 N.A. N.A.
Protein Similarity: N.A. N.A. N.A. 41.4 N.A. N.A.
P-Site Identity: N.A. N.A. N.A. 13.3 N.A. N.A.
P-Site Similarity: N.A. N.A. N.A. 33.3 N.A. N.A.
Phosphosite
Consensus
Position -7 -6 -5 -4 -3 -4 -5 0 +1 +2 +3 +4 +5 +6 +7
% Ala: 0 10 0 0 0 0 10 10 0 10 0 0 0 0 0 % A
% Cys: 0 37 0 0 0 0 0 0 0 0 0 0 0 19 0 % C
% Asp: 10 10 0 10 0 10 0 0 0 0 28 0 0 0 28 % D
% Glu: 0 0 10 10 0 46 19 10 0 37 0 0 0 0 10 % E
% Phe: 0 0 0 0 0 0 0 0 10 0 0 0 10 0 10 % F
% Gly: 0 10 0 0 0 0 0 0 0 0 10 0 10 0 0 % G
% His: 0 0 0 10 0 0 0 0 0 0 19 0 0 0 0 % H
% Ile: 0 0 10 0 10 0 0 0 0 0 0 0 0 0 0 % I
% Lys: 10 0 10 10 10 10 0 0 0 10 10 37 10 10 19 % K
% Leu: 0 0 19 0 0 0 10 0 82 19 0 10 0 37 10 % L
% Met: 37 10 0 10 0 0 37 10 0 0 10 10 0 0 0 % M
% Asn: 0 0 0 0 0 0 10 10 0 10 10 10 73 0 10 % N
% Pro: 19 0 10 0 19 19 0 0 0 10 0 10 0 0 10 % P
% Gln: 0 0 10 0 0 0 0 10 0 10 0 10 0 0 0 % Q
% Arg: 10 0 28 0 0 0 0 10 0 0 19 10 0 0 0 % R
% Ser: 10 19 0 10 55 0 19 0 10 0 0 10 0 19 0 % S
% Thr: 0 0 0 0 10 10 0 37 0 0 0 0 0 10 0 % T
% Val: 10 0 0 0 0 10 0 10 0 0 0 0 0 10 10 % V
% Trp: 0 0 0 10 0 0 0 0 0 0 0 0 0 0 0 % W
% Tyr: 0 10 10 37 0 0 0 0 0 0 0 0 0 0 0 % Y
% Spaces: 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 % _